Coalesix

In the world of drug discovery, pharmaceutical companies need to move quickly and efficiently from molecular structure exploration to candidate selection. Coalesix's Mobius Candidate Design Environment puts tools in scientists hands to help them custom craft millions of potential chemical entities, and rapidly isolate the most promising alternatives.

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Mobius provides a data-rich interface geared towards complex molecular exploration.

Coalesix's corporate tagline perfectly captures the challenge they brought to Filament Group with the user interface of their Mobius application: how could we "optimize intuition"?

Mobius is a pharmaceutical candidate design environment created to help drug discovery teams enable faster identification of more, and more viable, potential drug entities. Our challenge was to unify several distinct concurrent objectives — exploring and manipulating very complex chemistry, enabling a collaborative team environment where colleagues exchange and share information to build team-based portfolios of candidates, and tracking and annotating discoveries with a high-level of precision for patent documentation — in a powerful and intuitive user interface.

Coalesix knew they had a very different type of application and wanted the UI design to reflect that. The rich, layered interface system puts experiment data in the forefront, and minimizes navigation overhead and other UI clutter. At the same time, research scientists need robust tools to configure and customize their experiments; in a few clicks, the system provides workspaces to navigate an object's molecular structure, build highly-customized libraries of proprietary atomic fragments, randomize molecule components for exploration, identify bonding rules, and so on.

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Filament Group created a developer toolkit with detailed UI specifications.

Since the tool is most frequently employed by teams of researchers within organizations, it also includes a suite of collaborative tools where scientists can share ideas and use other's results as jumping off points to their work. Each researcher's annotations, notes and ideas can be tracked at an individual molecule or overall experiment level, and are automatically timestamped and aggregated in a virtual Bench Notebook. Users can easily share selected entries, while keeping others private.

As the Mobius tool was built as an installed software application rather than a web-based tool, Filament Group developed detailed specifications documentation of the visual and interaction system to help the developers translate the concepts into software.